Farnesyltransferase Inhibitors in Cancer Therapy 53 3 näher eingegangen wird

3 näher eingegangen wird

und die Ausübung dieser Kunst zu der Hauptbeschäftigung ihres Lebens machten

" (Alessandro Rossi

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(Poincaré)

Farnesyltransferase Inhibitors in Cancer Therapy 53 3 näher eingegangen wirdCutting edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farensyltransferase inhibitors (FTIs); geranylgeranyltransferase inhibitors (GGTIs) are also discussed as potential anticancer drugs. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other